Journal of Experimental Pharmacology (Feb 2024)
Pharmacological Activity of Chemical Compounds of Potato Peel Waste (Solanum tuberosum L.) in vitro: A Scoping Review
Abstract
Wahyu Hidayat,1,* Irna Sufiawati,1,* Mieke Hemiawati Satari,2,* Ronny Lesmana,3 Solachuddin Ichwan4 1Department of Oral Medicine, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia; 2Departmen of Oral Biology, Faculty of Medicine, Bandung Islamic University, Bandung, Indonesia; 3Department of Anatomy, Physiology and Biology Cell, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; 4Dentistry Programme PAPRSB, Institute of Health Sciences, Universiti of Brunei Darussalam, Bandar Seri Bagawan, Brunei Darussalam*These authors contributed equally to this workCorrespondence: Wahyu Hidayat, Email [email protected]: The potato (Solanum tuberosum L.) is a short-lived tuber plant with a round to oval shape and varying colors, depending on the variety. It is known that only the inside of the potato is used, while the peel is generally discarded. However, recent studies have shown that potato peels contain many health-beneficial compounds.Purpose: This study aimed to investigate the compounds present in potato peels and their in vitro activities.Methods: A scoping review following the PRISMA guidelines was conducted. The selection process involved identifying articles of in vitro research published within the last 10 years (2012– 2022). Electronic searches were conducted using the portals Scopus, ScienceDirect, EBSCOhost, and Portal Garuda by using the keywords “potato” or “Solanum tuberosum” and “peel” or “skin”. The search was limited to articles in English with full text availability.Results: The screening process resulted in a total of 4773 articles from the four search engines; 14 articles were obtained that met the requirements for the review, most of which use extract preparations in their research. Extracts of flavonoids, phenols, and glycoalkaloids are the most frequently studied compounds, and their antioxidant and anti-inflammatory activity have undergone extensive research.Conclusion: The potential compounds contained in potato peels, including flavonoids, phenols, and glycoalkaloids, are highly abundant and offer numerous benefits. Provides opportunities for further research to prove the potential pathway activity of the compound. These compounds have been the subject of extensive research, suggesting their significance in the context of health and nutrition.Keywords: flavonoid, peel, antioxidants, anti-inflammatory
