International Journal of General Medicine (Nov 2024)

Clinical Characteristics and Analysis of Risk Factors Associated with Rhabdomyolysis in Snakebite Victims

  • Wang FZ,
  • Xiang SH,
  • Lin SQ,
  • Qian FQ,
  • Zhang QX,
  • Geng MH,
  • Deng JX,
  • Wu SC

Journal volume & issue
Vol. Volume 17
pp. 5535 – 5546

Abstract

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Fu-zhen Wang,1,* Shi-hong Xiang,1,2,* Sen-qing Lin,1 Feng-qi Qian,1 Qiu-xia Zhang,1 Ming-hui Geng,1 Jin-xiu Deng,1 Sen-chao Wu1 1Department of Nephrology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, Fujian 364000, People’s Republic of China; 2Department of Nephrology, Xuanhan County People’s Hospital, Dazhou, Sichuan, 636150, People’s Republic of China*These authors contributed equally to this workCorrespondence: Sen-chao Wu; Jin-xiu Deng, Department of Nephrology, Longyan First Affiliated Hospital of Fujian Medical University, No.105 Jiuyi North Road, Longyan, Fujian, 364000, People’s Republic of China, Tel +86 13860217030 ; Tel +86 18159828598, Email [email protected]; [email protected]: To enhance the understanding of rhabdomyolysis (RM) caused by snakebites and to promptly identify and intervene in the risk factors associated with RM.Methods: A retrospective analysis involving 209 snakebite victims who visited our hospital for snakebite cases was conducted. Among these, 43 were related to RM, while 166 did not exhibit RM (NRM). The clinical characteristics, treatment, and prognostic outcomes of both groups were statistically analyzed, with the aim of interpreting the risk factors associated with snakebites concurrent with RM through logistic regression analysis.Results: Snakebite incidents commonly manifest during the summer and autumn seasons, predominantly affecting middle-aged and elderly populations, with injuries mostly occurring in the limbs. Creatine kinase (CK), CK isoenzyme MB, and lactate dehydrogenase indicators exhibited significantly elevated levels in the RM group compared to the NRM group (P 40 g/L were identified as protective factors against such occurrences.Conclusion: Snakebite victims with RM have more severe clinical conditions, necessitating prolonged treatment duration, and exhibit heightened mortality rates in comparison to those without RM.Keywords: acute kidney injury, clinical features, rhabdomyolysis, risk factors, snakebite

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