2-Furyl-6-nitro-1,2,4-triazolo [1,5-<i>a</i>]pyrimidin-7-one

Abstract

A sodium salt of 2-(fur-2-yl)-6-nitro-1,2,4-triazolo[1,5-a]pyrimidin-7-one as a close structural analogue of ZM-241385 was obtained. This heterocycle can serve as an effector for A2a adenosine receptors and possesses antiseptic activity. The structures of compounds were confirmed based on the data of 1H, 13C NMR spectroscopy, IR spectroscopy, and an elemental analysis. The structure of sodium salt 2-furyl-6-nitro-1,2,4-triazolo[1,5-a]pyrimidin-7-one was confirmed by an X-ray diffraction analysis.

Keywords

• azolo[1,5-<i>a</i>]pyrimidines
• nitrocompounds
• cyclization
• sepsis