Specific diagnostics of infectious and inflammatory osteoarticular disorders depending on HIV status of the patient

Abstract

The objective: to study the specific diagnostics of inflammatory lesions of the osteoarticular system depending on the patient's HIV status.Subjects and methods. The medical records of 166 patients with signs of inflammatory changes in the osteoarticular system were analyzed. Patients were divided into groups depending on their HIV status. Results. Tuberculosis was the major cause of osteoarticular inflammation in HIV positive patients (58.21%), while it was much less frequent in HIV negative patients (13.13%) (OR = 9.214; 95% CI 4.314; 19.680). HIV positive patients were found to have lower leukocyte counts (6.18 ± 0.24 per 109 cells/l versus 9.40 ± 0.43 per 109 cells/l in the group of HIV negative patients, p < 0.05). Tuberculous etiology of osteoarticular inflammation in patients with HIV infection was verified by microbiological methods in 43.3% of cases (95% CI 2.767; 13.472), and molecular genetic tests in 46.3% (95% CI2.722; 12.357). Invasive methods were used to obtain samples from the focus of inflammation.

Keywords

• вич
• туберкулез
• костно-суставная система
• диагностика
• воспалительное поражение