2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors

Abstract

Salivary gland tumors are a rare tumor entity within malignant tumors of all tissues. The most common are malignant mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic cell carcinoma. Pleomorphic adenoma is the most recurrent form of benign salivary gland tumor. Due to their low incidence rates and complex histological patterns, they are difficult to diagnose accurately. Malignant tumors of the salivary glands are challenging in terms of differentiation because of their variability in histochemistry and translocations. Therefore, the primary goal of the study was to review the current literature to identify the recent developments in histochemical diagnostics and translocations for differentiating salivary gland tumors.

Keywords

• salivary gland tumors
• epithelial salivary gland
• adenoid cystic carcinoma (ACC)
• pleomorphic adenoma
• mucoepidermoid carcinoma
• diagnostic markers