Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors

Marole Maria Maluleka; Malose Jack Mphahlele

doi:10.3390/proceedings2019022022

Proceedings (Aug 2019)

Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors

Marole Maria Maluleka,
Malose Jack Mphahlele

Affiliations

Marole Maria Maluleka: Department of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X06, Florida 1710, South Africa
Malose Jack Mphahlele: Department of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X06, Florida 1710, South Africa

DOI: https://doi.org/10.3390/proceedings2019022022
Journal volume & issue: Vol. 22, no. 1
p. 22

Abstract

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Nitrogen-containing heterocycles such as quinazolines and benzofurans have received a great amount of interest in targeted therapies as antitumor drugs [1]. [...]

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Published in Proceedings

ISSN: 2504-3900 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: General Works
Website: http://www.mdpi.com/journal/proceedings

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