The effectiveness of Irifrin 2.5 % and Irifrin-BK 2.5 % drugs in the treatment of computer vision syndrome

Abstract

Purpose: to assess the results of treatment of patients with computer visual syndrome (CVS) accompanied by low and mild myopia. Material and methods. 52 CVS patients aged 17 to 34 years (mean age 22.3 ± 2.72 years) were divided into 2 groups. For 4 weeks, patients in group 1 received Irifrin 2.5 % and patients in group 2 received preservative-free Irifrin-BK 2.5 % daily before going to bed. Before and after the course of treatment, all patients were examined to see how Irifrin 2.5 % and Irifrin-BK 2.5 % affect the main accommodation parameters: tear production, tear film stability and ocular surface epithelium. Results. The effectiveness of Irifrin 2.5 % medication was established for both pathogenetic links of CVS: disorders of accommodation and accommodative asthenopia related with it and the secondary “dry eye” syndrome. All patients demonstrated a decrease in the frequency and severity of asthenopia manifestations, increased uncorrected visual acuity, the absolute accommodation volume, as well as positive and negative parts of volume relative accommodation volume, which can be associated with the effect produced by phenylephrine hydrochloride. Besides, a reduction of the subjective discomfort is noted. Corneal epithelial staining with sodium fluorescein and conjunctiva staining with rose Bengal solution becomes less pronounced. Precorneal tear film demonstrates increased stability. These effects are apparently due to the presence of hydroxypropylmethyl cellulose in both drugs and the absence of preservative in Irifrin-BK 2.5 % // Russian Ophthalmological Journal, 2017; 1: 74-9. doi: 10.21516/2072-0076-2017-10-1-74-79.

Keywords

• компьютерный зрительный синдром
• синдром сухого глаза
• аккомодация
• ирифрин
• ирифрин-бк
• computer visual syndrome
• dry eye syndrome
• accommodation
• irifrin
• irifrin-bk