Nature Communications (Nov 2017)

Microbial volatile communication in human organotypic lung models

  • Layla J. Barkal,
  • Clare L. Procknow,
  • Yasmín R. Álvarez-García,
  • Mengyao Niu,
  • José A. Jiménez-Torres,
  • Rebecca A. Brockman-Schneider,
  • James E. Gern,
  • Loren C. Denlinger,
  • Ashleigh B. Theberge,
  • Nancy P. Keller,
  • Erwin Berthier,
  • David J. Beebe

DOI
https://doi.org/10.1038/s41467-017-01985-4
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 10

Abstract

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There is a need for improved in vitro models of host-microbe interactions in the lung. Here, Barkal et al. present a microscale organotypic model of the human bronchiole for studying pulmonary infection, including volatile compound communication between microbial populations and host cells.