A Comparison of Clinical Efficacy of Dentifrices Containing Calcium Sodium Phosphosilicate, Nanoparticle Hydroxyapatite and a Dentifrice Containing Casein Phosphopeptide Amorphous Calcium Phosphate on Dentinal Hypersensitivity- A Comparative Triple Blind Randomized Study

Abstract

Aim : A considerable number of agents are effective in the treatment of dentin hypersensitivity. This3 month randomized clinical trial compares a dentifrice containing Calcium Sodium Phosphosilicate, Nanoparticle Hydroxyapatite and Casein Phosphopeptide-Amorphous Calicium Phosphate. Materials and Method : Eighty teeth were selected in each group. The volunteers selected at baseline had a history of dentin hypersensitivity caused by gingival recession or after scaling and root planing. Patients were evaluated for dentin hypersensitivity using visual analog score and Schiff test. Patients were required to have a visual analog scale score of ‡2 to be included in the study. After sensitivity scores for controlled air stimulus and cold water at baseline were recorded, subjects were given toothpastes randomly and sensitivity scores were measured again at 2nd week, 4th week, 2nd month and 3rd month. Results : All three groups showed reduction in sensitivity scores at 2weeks, 4 weeks and at 3 months for air stimulus and cold water. The nanoparticle hydroxyapatite group was found to be significantly better in reducing the visual analog scale score as well as Schiff test score and at any time point for both measures of sensitivity. Conclusion : The Nanoparticle Hydroxyapatite group showed comparable reduction in the symptoms of dentin hypersensitivity.

Keywords

• Dentifrices
• Dentin hypersensitivity
• Biocompatible materials.