Журнал инфектологии (Apr 2022)

Clinical case of COVID-19 course in a child with aplastic anemia

  • D. O. Ivanov,
  • Yu. V. Petrenko,
  • R. A. Nasyrov,
  • V. A. Reznik,
  • V. N. Timchenko,
  • T. A. Kaplina,
  • S. L. Bannova,
  • O. L. Krasnogorskaya,
  • M. B. Paneyakh,
  • E. P. Fedotova,
  • G. V. Kondratyev,
  • M. D. Subbotina,
  • M. A. Shakmaeva

DOI
https://doi.org/10.22625/2072-6732-2022-14-1-145-151
Journal volume & issue
Vol. 14, no. 1
pp. 145 – 151

Abstract

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The problem of the non-smooth course of COVID-19 and deaths in children with severe comorbid pathology is urgent. Among all registered cases of a new coronavirus infection in the Russian Federation, children account for up to 8,6%, of which severe forms are noted, as a rule, in patients with concomitant diseases. A clinical observation of the course of a new coronavirus infection in a child with a severe form of idiopathic aplastic anemia complicated by pancytopenia is presented. COVID-19 infection caused a sharp deterioration in the child’s condition. Despite the use of modern methods of therapy, there was a rapid deterioration of clinical and laboratory parameters: an increase in febrility, respiratory failure, interstitial changes in the lungs, a decrease in oxygen saturation to 70%, hemorrhagic, anemic syndromes and multiple organ failure with the development of a fatal outcome. Aplastic anemia is a factor predisposing to the severe course of COVID-19 and contributing to an unfavorable outcome.

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