Nature Communications (Apr 2019)
Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients
- Xu-Chao Zhang,
- Jun Wang,
- Guo-Guang Shao,
- Qun Wang,
- Xiaotao Qu,
- Bo Wang,
- Christopher Moy,
- Yue Fan,
- Zayed Albertyn,
- Xiayu Huang,
- Jingyu Zhang,
- Yang Qiu,
- Suso Platero,
- Matthew V. Lorenzi,
- Enrique Zudaire,
- Jennifer Yang,
- Ying Cheng,
- Lin Xu,
- Yi-Long Wu
Affiliations
- Xu-Chao Zhang
- Guangdong Lung Cancer Institute, Guangdong Provincial People’s Hospital and Guangdong Academy of Medical Sciences
- Jun Wang
- Peking University People’s Hospital
- Guo-Guang Shao
- Thoracic Surgery, 1st Hospital of Jilin University
- Qun Wang
- Zhongshan Hospital, Fudan University
- Xiaotao Qu
- Janssen R&D China
- Bo Wang
- Janssen R&D China
- Christopher Moy
- Janssen R&D
- Yue Fan
- Janssen R&D China
- Zayed Albertyn
- Novocraft Technologies
- Xiayu Huang
- Janssen R&D China
- Jingyu Zhang
- Janssen R&D China
- Yang Qiu
- Janssen R&D China
- Suso Platero
- Janssen R&D
- Matthew V. Lorenzi
- Janssen R&D
- Enrique Zudaire
- Janssen R&D
- Jennifer Yang
- Janssen R&D China
- Ying Cheng
- Department of Medical Oncology, Jilin Provincial Cancer Hospital
- Lin Xu
- Department of Thoracic Surgery, Nanjing Medical University Affiliated Cancer Hospital, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Cancer Institute of Jiangsu Province
- Yi-Long Wu
- Guangdong Lung Cancer Institute, Guangdong Provincial People’s Hospital and Guangdong Academy of Medical Sciences
- DOI
- https://doi.org/10.1038/s41467-019-09762-1
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 12
Abstract
The relationship between genomic alteration and immune context in non-small cell lung cancer (NSCLC) is complex. Here, the authors analyse the molecular and immunological landscape of 245 Chinese patients with NSCLC and find low immune infiltration correlates with genomic alterations.
