Crystal structure of 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one

Abstract

The title compound, C22H16N2O2 {systematic name: 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one}, consists of a substituted 2-[(E)-2-arylethenyl]-3-arylquinazolin-4(3H)-one skeleton. The substituents at the ethylene fragment are located in trans positions. The phenyl ring is inclined to the quinazolone ring by 26.44 (19)°, while the 4-hydroxyphenyl ring is inclined to the quinazolone ring by 81.25 (8)°. The phenyl ring and the 4-hydroxyphenyl ring are inclined to one another by 78.28 (2)°. In the crystal, molecules are connected via O—H...O hydrogen bonds, forming a helix along the a-axis direction. The helices are linked by C—H...π interactions, forming slabs parallel to (001).

Keywords

• crystal structure
• 2,3-disubstituted quinazolin-4(3H)-one
• styrylquinazolinone conjugation system
• hydrogen bonding