711 IGM-7354 is an anti-PD-L1 IgM antibody and IL-15 cytokine fusion that enhances NK and CD8+ T cell proliferation and tumor cytotoxicity plus potently reverses T cell exhaustion

• Maya Kotturi,
• Mélanie Desbois,
• Angus Sinclair,
• Thierry Giffon,
• Dean Ng,
• Poonam Yakkundi,
• Marigold Manlusoc,
• Rodnie Rosete,
• Avneesh Saini,
• Bruce Keyt,
• Daniel Machado,
• Miho Oyasu,
• Susan Calhoun,
• Tasnim Kothambawala,
• Beatrice Wang

Affiliations

Maya Kotturi

Aff39 Compugen Inc, USA South San Francisco CA USA

Mélanie Desbois

Analyse Moléculaire, Modélisation et Imagerie de la Maladie Cancéreuse, Laboratoire d’Immunomonitoring en Oncologie, Gustave Roussy Institute, INSERM, CNRS, Paris-Saclay University, Villejuif, Île-de-France, France

Angus Sinclair

IGM Biosciences, Mountain View, CA, USA

Thierry Giffon

IGM Biosciences, Mountain View, CA, USA

Dean Ng

IGM Biosciences, Mountain View, CA, USA

Poonam Yakkundi

IGM Biosciences, Mountain View, CA, USA

Marigold Manlusoc

IGM Biosciences, Mountain View, CA, USA

Rodnie Rosete

IGM Biosciences, Mountain View, CA, USA

Avneesh Saini

IGM Biosciences, Mountain View, CA, USA

Bruce Keyt

IGM Biosciences, Mountain View, CA, USA

Daniel Machado

2 Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA

Miho Oyasu

IGM Biosciences Inc, Mountain View, CA, United States

Susan Calhoun

IGM Biosciences Inc, Mountain View, CA, United States

Tasnim Kothambawala

IGM Biosciences Inc, Mountain View, CA, United States

Beatrice Wang

IGM Biosciences Inc, Mountain View, CA, United States