Generation of a human induced pluripotent stem cell line (SHUPLi002-A) from PBMCs of a healthy female donor

Beixu Li; Xing Ye; Junyi Lin; Kaijun Ma; Meng He; Youxin Fang

Stem Cell Research (Jun 2024)

Generation of a human induced pluripotent stem cell line (SHUPLi002-A) from PBMCs of a healthy female donor

Beixu Li,
Xing Ye,
Junyi Lin,
Kaijun Ma,
Meng He,
Youxin Fang

Affiliations

Beixu Li: School of Policing Studies, Shanghai University of Political Science and Law, Shanghai, China; Shanghai Fenglin Forensic Center, Shanghai, China
Xing Ye: Department of Forensic Medicine, School of Basic Medical Sciences, Gannan Medical University, Jiangxi, China
Junyi Lin: Department of Forensic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, China
Kaijun Ma: Shanghai Key Laboratory of Crime Scene Evidence, Institute of Forensic Science, Shanghai Public Security Bureau, Shanghai, China
Meng He: Department of Forensic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, China; Corresponding authors.
Youxin Fang: Department of Neurology, Minhang Hospital, Fudan University, Shanghai, China; Corresponding authors.

Journal volume & issue: Vol. 77
p. 103422

Abstract

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Human induced pluripotent stem cells (iPSCs) have good multi-lineage differentiation potential, which is an ideal model for studying the pathogenesis of diseases and drug screening.Here, we generated an iPSC line, SHUPLi002-A, from peripheral blood mononuclear cells (PBMCs) of a healthy 28-year-old female individual using episomal vectors. SHUPLi002-A is characterized by expression of classical pluripotent stem cell markers as well as teratoma formation assays to evaluate their differentiation capacity in vivo.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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