Hematology, Transfusion and Cell Therapy (Jul 2023)

Dentistry consensus on HSCT – Part III: Special topics – Dentistry on HSCT

  • Paulo Sérgio da Silva Santos,
  • Fabiana Caramori Noal Granzotto,
  • Héliton Spindola Antunes,
  • Emilze Mafra de Lima,
  • Renata de Freitas Varanda,
  • Karina Maccari,
  • Leticia Mello Bezinelli,
  • Walmyr Ribeiro Melo,
  • Luiz Alberto Valente Soares Junior,
  • Leandro Dorigan De Macedo,
  • Fernanda de Paula Eduardo

Journal volume & issue
Vol. 45, no. 3
pp. 379 – 386

Abstract

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Patients undergoing hematopoietic stem cell transplantation (HSCT) might present acute and late toxicities and the oral tissues are frequently affected. With the survival increasing, patients show late and long-term morbidities, and there is an important association between the general and the oral health. The first and second parts of this Consensus have showed the importance of the adequacy of oral health in the pre-HSCT, and the main alterations and oral care during the period of admission for HSCT. This third part aims to review specific themes of post-HSCT dental care, such as graft-versus-host disease (GVHD) and the pediatric patient. It also aims to review pertinent subjects, both during the HSCT period and post-HSCT, concerning quality of life, pain, cost-effectiveness, and remote care. Based on this review, it is evident the importance of the work of the dental surgeon (DS) in the follow-up and treatment of the HSCT patient, always collaborating with the whole multidisciplinary team.

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