Nature Communications (Apr 2020)
Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle
- Wai Yee Low,
- Rick Tearle,
- Ruijie Liu,
- Sergey Koren,
- Arang Rhie,
- Derek M. Bickhart,
- Benjamin D. Rosen,
- Zev N. Kronenberg,
- Sarah B. Kingan,
- Elizabeth Tseng,
- Françoise Thibaud-Nissen,
- Fergal J. Martin,
- Konstantinos Billis,
- Jay Ghurye,
- Alex R. Hastie,
- Joyce Lee,
- Andy W. C. Pang,
- Michael P. Heaton,
- Adam M. Phillippy,
- Stefan Hiendleder,
- Timothy P. L. Smith,
- John L. Williams
Affiliations
- Wai Yee Low
- The Davies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide
- Rick Tearle
- The Davies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide
- Ruijie Liu
- The Davies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide
- Sergey Koren
- Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute
- Arang Rhie
- Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute
- Derek M. Bickhart
- Dairy Forage Research Center, ARS USDA
- Benjamin D. Rosen
- Animal Genomics and Improvement Laboratory, ARS USDA
- Zev N. Kronenberg
- Phase Genomics
- Sarah B. Kingan
- Pacific Biosciences
- Elizabeth Tseng
- Pacific Biosciences
- Françoise Thibaud-Nissen
- National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health
- Fergal J. Martin
- European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus
- Konstantinos Billis
- European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus
- Jay Ghurye
- Center for Bioinformatics and Computational Biology, Lab 3104A, Biomolecular Science Building, University of Maryland
- Alex R. Hastie
- Bionano Genomics
- Joyce Lee
- Bionano Genomics
- Andy W. C. Pang
- Bionano Genomics
- Michael P. Heaton
- US Meat Animal Research Center, ARS USDA
- Adam M. Phillippy
- Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute
- Stefan Hiendleder
- The Davies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide
- Timothy P. L. Smith
- US Meat Animal Research Center, ARS USDA
- John L. Williams
- The Davies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide
- DOI
- https://doi.org/10.1038/s41467-020-15848-y
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 14
Abstract
Taurine and indicine cattle have different desirable traits making them better adapted to different climates across the world. Here, Low et al. describe a pipeline to produce haplotype-resolved, chromosome-level genomes of Angus and Brahman cattle breeds from a crossbred individual and report on comparisons of the two genomes.
