Nature Communications (Aug 2018)

Gating of miRNA movement at defined cell-cell interfaces governs their impact as positional signals

  • Damianos S. Skopelitis,
  • Kristine Hill,
  • Simon Klesen,
  • Cristina F. Marco,
  • Patrick von Born,
  • Daniel H. Chitwood,
  • Marja C. P. Timmermans

DOI
https://doi.org/10.1038/s41467-018-05571-0
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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Movement of small RNA between cells is critical to plant development and stress responses. Here the authors uncover a gate-keeping mechanism that can restrict small RNA movement at cell-cell interfaces, providing selectivity in long-distance signalling and limiting the scope of local mobility.