Journal of Investigative Medicine High Impact Case Reports (Jul 2024)

A Rare Case of Primary B-Cell Lymphoma of the Pancreas

  • Dayana Nasr MD,
  • John Joyce MBBS,
  • Vishnu Kumar MBBS,
  • Hafiz M. Khan MD,
  • Savio John MD,
  • Sidhartha Chaudhry MD

DOI
https://doi.org/10.1177/23247096241263536
Journal volume & issue
Vol. 12

Abstract

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Primary pancreatic lymphomas (PPLs) are a subgroup of gastrointestinal (GI) lymphomas. They are an exceedingly rare entity, both in terms of pancreatic malignancies and also extranodal lymphomas. Epidemiological investigations have been challenging to do because of their rarity. This has resulted in a lack of clarity on the clinicopathological characteristics, differential diagnosis, best course of treatment, and prognosis of PPL. Because the clinical signs are frequently non-specific, it can lead to a diagnostic hazard for the unwary physician. Preoperatively, it is imperative to distinguish between adenocarcinoma and PPL, as they present similarly, but have vastly different treatment modalities and prognosis. We herein present a case of an elderly man who presented with obstructive jaundice and was found to have PPL.