THE SURVIVAL RATE OF PATIENTS FOLLOWING UVEAL MELANOMA EYEBALL REMOVAL IN PERM REGION

Abstract

Objective — analysis of survival rate among the patients with uveal melanoma eyeball removal in Perm Region. patients and methods. Retrospective analysis of medical documentation of 108 patients treated in ophthalmologic departments in the cit y of Perm has been carried out. Patients have undergone the surgery for uveal melanoma eyeball enucleation (2005–2014).Results. Analytic period involved 108 uveal melanoma eyeball removal in 108 patients aged 17–89 (61,61,6 years in average). There were 61 (56,5%) women and 47 (43,5%) men. Practical blindness was identified in 63,8% eyes, and in remaining eyes it was detected in 0,005–1,0 cases. Melanoma was localized in choroid in 79,6%; ciliary body — 10,2%; iris — 4,6%; and ciliary body and iris — 5,6%. Histology revealed mixed cell form in 68,5% cases; sarcomatoid form — 28,7%; epithelioid cell form — 2,8%. The outcome was determined in 99 (91,7%) patients. Follow-up period was from 6 months to 10 years after enucleation. Among those 27 (27,3%) patients died within the analytic period. Five-year survival rate was observed in 79,8% patients with average lifespan 3,4 yrs. Cause of death was established in 19 (70,4%) individuals. Association with oncologic diseases was determined in 6 (31,6%), and non-oncologic in 13 (68,4%) subjects.Conclusion. At the place of residence life-long observation by ophthalmologist and oncologist is essential for these patients. Outpatient physicians should have oncologic alertness while working with patients of any age for early diagnosis of eye neoplasm.

Keywords

• увеальная меланома
• энуклеация
• выживаемость
• метастазы
• продолжительность жизни