Exploratory Animal and Medical Research (Dec 2014)
HAEMOGLOBIN PHENOVARIANTS VS RESILIENCE STATUS, HAEMATOLOGICAL, BIOCHEMICAL AND MINERAL PROFILE IN GAROLE SHEEP NATURALLY INFECTED WITH HAEMONCHUS CONTORTUS.
Abstract
A total of 232 nos. of Garole sheep were evaluated for studying the variability of resilience to natural infection of Haemonchus contortus in relation to haemoglobin phenovariants as well as to know the association of haemoglobin phenovariants with several haematological parameters, biochemical parameters and serum macro and micro elements. This study revealed a significant variation (p<0.01) of haematological parameters, biochemical parameters and mineral status against resistance status and haemoglobin phenovariants. Significantly (P<0.01) less EPG count was recorded in Haemoglobin–AB type animals than the Haemoglobin-BB type animals. Haemoglobin-AB type animals also possessed significantly higher level of haemoglobin, packed cell volume, total leukocyte count, lymphocyte count, serum total protein, albumin, globulin, calcium, phosphorus, iron, copper and zinc than Haemoglobin-BB type animals. On the other hand Haemoglobin-BB type animals possessed significantly higher level of neutrophil and serum alkaline phosphatase enzyme than Haemoglobin-AB type animals. During selection of H. contortus resistant Garole sheep inclusion of haemoglobin type as an indicator trait may be helpful to achieve the goal. Measurement of haematological parameters, biochemical parameters and serum macro and micro elements in these cases may also be essential for diagnostic and therapeutic purposes