LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast

Abstract

A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe.