Nature Communications (Jun 2020)

Direct observation of independently moving replisomes in Escherichia coli

  • Aleksandre Japaridze,
  • Christos Gogou,
  • Jacob W. J. Kerssemakers,
  • Huyen My Nguyen,
  • Cees Dekker

DOI
https://doi.org/10.1038/s41467-020-16946-7
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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How chromosome replication and segregation is organised in E. coli is a matter of debate. Here the authors visualise the bacterial chromosome and the replisomes during DNA replication, providing support for a previously suggested train track model.