International Journal of Molecular Sciences (Sep 2023)

mTOR Signaling: New Insights into Cancer, Cardiovascular Diseases, Diabetes and Aging

  • Anindita Das,
  • Flávio Reis

DOI
https://doi.org/10.3390/ijms241713628
Journal volume & issue
Vol. 24, no. 17
p. 13628

Abstract

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The mechanistic/mammalian target of rapamycin (mTOR), a member of the phosphoinositide 3-kinase (PI3K) related kinase family, integrates intracellular and environmental cues that coordinate a diverse set of cellular/tissue functions, such as cell growth, proliferation, metabolism, autophagy, apoptosis, longevity, protein/lipid/nucleotide synthesis, and tissue regeneration and repair [...]

Keywords