Can troxerutin pretreatment prevent testicular complications in prepubertal diabetic male rats?

Abstract

Objective. The vast majority of type 1 diabetes leads to a higher prevalence of reproductive system’s impairments. Troxerutin has attracted much attention owing to its favorable properties, including antihyperglycemic, anti-inflammatory, and antiapoptotic effects. This investigation was proposed to evaluate whether pretreatment with troxerutin could prevent apoptosis-induced testicular disorders in prepubertal diabetic rats.

Keywords

• troxerutin
• diabetes
• testis
• apoptosis
• oxidative stress