Revista Cubana de Medicina Militar (Jun 2022)

Heberprot-P in the treatment of diabetic foot ulcers

  • Saymara Castillo Deprés,
  • Mothabeng Thabo Geoffrey,
  • Lotty Ledwaba,
  • Thula K. Ngcobo,
  • Natasha Singh MMed,
  • Julio Esmir Baldomero Hernández,
  • Ana Blanca Torres Minkova,
  • Osvaldo Reyes Acosta,
  • Dania Castillo Deprés

Journal volume & issue
Vol. 51, no. 3
pp. e02201923 – e02201923

Abstract

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Introduction: The diabetic foot is one of the most feared complications of diabetes mellitus; It is the cause of 80 % of non-traumatic amputations worldwide. For decades, different treatments have been used to heal diabetic foot; growth factors have revolutionized this therapy. The participation of a multidisciplinary team with compliance with the action protocols and the use of Heberprot-P decrease the rate of amputations in patients with this condition. Objective: To present the evolution of patients with diabetic foot ulcers, in different clinical stages, treated with Heberprot-P. Development: Three clinical cases are presented; The first is a male patient, 56 years old, diabetic, with open transmetatarsal amputation in which 16 applications of Heberprot-P were performed and a skin graft was placed, the lesion closed in 45 days. The second is a 58-year-old patient, diabetic and hypertensive, with a right foot injury, with previous vascular surgery; 19 applications of Heberprot-P were performed and the lesion healed in 49 days. The third case is a 55-year-old patient, who was admitted due to an extensive injury to his right foot, 22 applications of Heberprot-P were performed, closure of the injury was achieved in 85 days and amputation was avoided. Conclusions: The presented cases evolved favorably with Heberprot-P treatment.

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