Nature Communications (Nov 2018)
Disease-associated genotypes of the commensal skin bacterium Staphylococcus epidermidis
- Guillaume Méric,
- Leonardos Mageiros,
- Johan Pensar,
- Maisem Laabei,
- Koji Yahara,
- Ben Pascoe,
- Nattinee Kittiwan,
- Phacharaporn Tadee,
- Virginia Post,
- Sarah Lamble,
- Rory Bowden,
- James E. Bray,
- Mario Morgenstern,
- Keith A. Jolley,
- Martin C. J. Maiden,
- Edward J. Feil,
- Xavier Didelot,
- Maria Miragaia,
- Herminia de Lencastre,
- T. Fintan Moriarty,
- Holger Rohde,
- Ruth Massey,
- Dietrich Mack,
- Jukka Corander,
- Samuel K. Sheppard
Affiliations
- Guillaume Méric
- The Milner Centre for Evolution, University of Bath
- Leonardos Mageiros
- The Milner Centre for Evolution, University of Bath
- Johan Pensar
- Department of Mathematics and Statistics, University of Helsinki
- Maisem Laabei
- The Milner Centre for Evolution, University of Bath
- Koji Yahara
- Antimicrobial Resistance Research Center, National Institute of Infectious Diseases
- Ben Pascoe
- The Milner Centre for Evolution, University of Bath
- Nattinee Kittiwan
- Integrative Research Centre for Veterinary Preventive Medicine, Faculty of Veterinary Medicine, Chiang Mai University
- Phacharaporn Tadee
- Graduate School, Maejo University
- Virginia Post
- AO Research Institute Davos
- Sarah Lamble
- Wellcome Centre for Human Genetics, University of Oxford
- Rory Bowden
- Wellcome Centre for Human Genetics, University of Oxford
- James E. Bray
- Department of Zoology, University of Oxford
- Mario Morgenstern
- Department of Orthopaedic Surgery and Traumatology, University Hospital Basel
- Keith A. Jolley
- Department of Zoology, University of Oxford
- Martin C. J. Maiden
- Department of Zoology, University of Oxford
- Edward J. Feil
- The Milner Centre for Evolution, University of Bath
- Xavier Didelot
- Department of Infectious Disease Epidemiology, Imperial College
- Maria Miragaia
- Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa
- Herminia de Lencastre
- Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa
- T. Fintan Moriarty
- AO Research Institute Davos
- Holger Rohde
- Institut für Medizinische Mikrobiologie, Virologie & Hygiene, Universität Hamburg
- Ruth Massey
- The Milner Centre for Evolution, University of Bath
- Dietrich Mack
- Bioscientia Labor Ingelheim, Institut für Medizinische Diagnostik GmbH
- Jukka Corander
- Department of Mathematics and Statistics, University of Helsinki
- Samuel K. Sheppard
- The Milner Centre for Evolution, University of Bath
- DOI
- https://doi.org/10.1038/s41467-018-07368-7
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 11
Abstract
Staphylococcus epidermidis is carried asymptomatically by virtually all humans but is also a major cause of nosocomial infection. Here, the authors study 141 isolates from healthy carriage and 274 isolates from clinical infections, and identify genes and genetic elements associated with pathogenicity.
