مجلة كلية الطب (Apr 2007)

Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients

  • Yacoob Y. Al-Rubayei,
  • Batool A. Al-Haidary,
  • Wala'a E. Jasim

Journal volume & issue
Vol. 49, no. 1

Abstract

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Background: Asthma is an allergic hypersensitivity disease in which many mediators play a role in its pathogenecity. One of these etiological agents is the mediators such as Interleukin-5 (IL-5). The aim of this study to demonstrate the association between IL-5 and obesity in asthma development. Materials & Methods: One hundred and four sera samples for asthma cases have been studied in comparison with 41 non-asthmatic bronchitis as a patient controls beside 30 apparently healthy controls. Cytokine has been estimated using ELISA method in correlation with Body Mass Index (BMI). Results: This study revealed a significant correlation between IL-5 concentration and BMI (P<0.05), particularly among females. Conclusion: There is certain correlation between obesity and asthma accompanied by IL-5.

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