Effectiveness of Farnesol for treatment of dog otitis complicated by Malassezia pachydermatis

Abstract

The study involved 30 dogs with otitis complicated by Malassezia pachydermatis . The animals were divided into 2 groups: experimental (n = 15) and control (n = 15). The experimental group was prescribed veterinary ear drops Surolan + a solution of the drug Farnesol; the control group - Surolan. The study showed that when Farnesol is added to the treatment regimen for fungal otitis etiology in dogs, small changes in the clinical composition of the blood are recorded, characterized by an increase in the number of erythrocytes and hemoglobin, a decrease in the number of leukocytes, with a decrease in the indicators of eosinophils and rod-shaped neutrophils in the experiment compared with the control. In addition, the complete absence of Malassezia pachydermatis in the smears of the ear contents after two weeks of therapy with a combined drug was proved. That is, in the experimental group, there were no cases of the presence of yeast-like fungi (YLF) in the smear after combined therapy with Surolan + Farnesol. And in the control group of 15 animals, YLF were observed in two with microscopy of ear exudate smears, but not in high concentration. The use of a combination of Surolan and Farnesol in dogs of the experimental group led to a decrease in hyperemia, itching, edema, ear fetid fluid on the 5th7th days of treatment, and complete clinical recovery of the animals occurred by the 10th14th day of therapy. In the control group, only Surolan was used, and improvement of clinical condition occurred on days 1214, and recovery only after completion of the full course. As a result, both treatment regimens were successful, but the scheme with Farnesol gave faster results due to the wide spectrum of action of this drug: both antimicrobial and anti-inflammatory.

Keywords

• yeast-like fungi
• mycosis
• clinical blood test
• phytotherapy
• surolan