Current approaches to the diagnosis of autoimmune bullous dermatoses

Abstract

A modern review of highly effective methods for the diagnosis of autoimmune bullous dermatoses are presented. The specificity of the production of autoantibodies underlying bullous dermatoses are described. Considering the severity of the disease and a significant deterioration in the quality of life of patients suffering from bullous dermatoses; the systematization of diagnostic criteria will help improve the prognosis and management of patients; and it will also help optimize work on the development of targeted drugs for the treatment of patients with this pathology.

Keywords

• pemphigus
• pemphigoid
• desmoglein
• desmocollin
• pectin
• bp180
• bp230
• collagen type vii
• laminin
• deamidated gliadin
• tissue transglutaminase
• antigenic epitopes
• biochip
• multivariate elisa