MODERN METHODS OF INDENTIFYING THE PREDICTORS OF CARDIO-VASCULAR DISEASES IN CHILDREN AT EARLY STAGES

Abstract

Cardiovascular diseases are the main cause of invalidism and untimely death of people in developed countries. The share of cardiovascular diseases in the mortality rate reaches 40-60%. The frequency rate of cardiovascular diseases among children and adolescents is growing with each passing year. Increased blood pressure variability in patients with arterial hypertension in youth is a factor aggravating the arterial stiffness derangement. The aim of this study is to develop methods of early cardiovascular diseases’ diagnostics in children in order to reduce the rate of primary and repeated complications in the future. Observation showed that singular blood pressure measurements at a consultative appointment with a doctor do not give the full picture of the character of its changes in a child and may lead to incorrect diagnosis, as blood pressure has considerable individual variability. Daily blood pressure monitoring allowed revealing high arterial hypertension rate in children at night, including children with normal and low blood pressure during daytime. It is shown that the non-invasive oscillometric arteriography method allows to determine parameters characterizing arterial vessels’ remodeling with a high reproducibility. Significant difference between the obesity degree and the pulse wave aortic spread speed increase has been indentified.

Keywords

• cardiovascular diseases
• atherosclerosis
• children
• blood pressure
• daily blood pressure monitoring
• non-invasive arteriography
• pulse wave’s aortic spread speed
• augmentation index