Interferon α-induced SAMHD1 regulates human cultured megakaryocyte apoptosis and proplatelet formation

• Seema Bhatlekar,
• Shancy Jacob,
• Emilia Tugolukova,
• Bhanu K. Manne,
• Yasuhiro Kosaka,
• Phillipe Loher,
• Ryan M. O’Connell,
• Vicente Planelles,
• Matthew T. Rondina,
• Isidore Rigoutsos,
• Paul F. Bray

Affiliations

Seema Bhatlekar

Program in Molecular Medicine and Department of Internal Medicine, University of Utah, Salt Lake City

Shancy Jacob

Program in Molecular Medicine and Department of Internal Medicine, University of Utah, Salt Lake City

Emilia Tugolukova

Program in Molecular Medicine and Department of Internal Medicine, University of Utah, Salt Lake City

Bhanu K. Manne

Program in Molecular Medicine and Department of Internal Medicine, University of Utah, Salt Lake City, UT

Yasuhiro Kosaka

Program in Molecular Medicine and Department of Internal Medicine, University of Utah, Salt Lake City

Phillipe Loher

Computational Medicine Center, Thomas Jefferson University, Philadelphia

Ryan M. O’Connell

Division of Microbiology and Immunology, Department of Pathology, and Huntsman Cancer Institute, University of Utah Health Sciences Center, University of Utah, Salt Lake City

Vicente Planelles

Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City

Matthew T. Rondina

Program in Molecular Medicine and Department of Internal Medicine, University of Utah, Salt Lake City, UT; Department of Pathology, University of Utah, Salt Lake City, UT and the George E. Wahlen VAMC Department of Medicine and George E. Wahlen VAMC GRECC, Salt Lake City

Isidore Rigoutsos

Department of Pathology, University of Utah, Salt Lake City, UT and the George E. Wahlen VAMC Department of Medicine and George E. Wahlen VAMC GRECC, Salt Lake City

Paul F. Bray

Program in Molecular Medicine and Department of Internal Medicine, University of Utah, Salt Lake City, UT; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, University of Utah, Salt Lake City