Acute adrenal insufficiency due to paracoccidiodomycosis. Report of 2 cases

Abstract

Paracoccidiodomycosis s is an endemic infection in Latin America. It can affect several organs, but systemic involvement is rare, especially when the adrenal glands and the central nervous system are affected. We describe two cases of paracoccidiodomycosis presenting with Addison’s disease, one of which also presented with a pseudotumor cerebri. The diagnosis of paracoccidiodomycosis was confirmed in both cases with histopathological studies. Antifungal management and hormone supplementation were given, achieving complete resolution of symptoms. 2012 Elsevier Ltd. All rights reserved.

Keywords

• Adrenal insufficiency
• Brain tumour
• Immunocompetent
• Disseminated paracoccidiodomycosis