P619: TARGETING TRANSLATION BY DISRUPTING THE NEWLY IDENTIFIED PROHIBITIN-EIF4F COMPLEX AS A NOVEL THERAPEUTIC STRATEGY IN CHRONIC LYMPHOCYTIC LEUKEMIA

• A. Largeot,
• V. Klapp,
• S. Gonder,
• E. Viry,
• M. Szpakowska,
• D. Perez Hernandez,
• G. Dittmar,
• A. Chevigné,
• L. Ysebaert,
• B. Stamatopoulos,
• L. Desaubry,
• J. Paggetti,
• E. Moussay

Affiliations

A. Largeot

1 Department of Cancer Research, Luxembourg Institute of Health, Luxembourg

V. Klapp

1 Department of Cancer Research, Luxembourg Institute of Health, Luxembourg

S. Gonder

1 Department of Cancer Research, Luxembourg Institute of Health, Luxembourg

E. Viry

1 Department of Cancer Research, Luxembourg Institute of Health, Luxembourg

M. Szpakowska

2 Department of Infection and Immunity, Luxembourg Institute of Health, Esch sur Alzette, Luxembourg

D. Perez Hernandez

2 Department of Infection and Immunity, Luxembourg Institute of Health, Esch sur Alzette, Luxembourg

G. Dittmar

2 Department of Infection and Immunity, Luxembourg Institute of Health, Esch sur Alzette, Luxembourg

A. Chevigné

2 Department of Infection and Immunity, Luxembourg Institute of Health, Esch sur Alzette, Luxembourg

L. Ysebaert

3 Service d’Hématologie, IUCT-Oncopole, Toulouse, France

B. Stamatopoulos

4 Laboratory of Clinical Cell Therapy, ULB-Research Cancer Center (U-CRC), Jules Bordet Institute Université Libre de Bruxelles, Brussels, Belgium

L. Desaubry

5 Regenerative Nanomedicine Laboratory (UMR1260), Faculty of Medicine, FMTS, INSERM-University of Strasbourg, Strasbourg, France

J. Paggetti

1 Department of Cancer Research, Luxembourg Institute of Health, Luxembourg

E. Moussay

1 Department of Cancer Research, Luxembourg Institute of Health, Luxembourg