Mutational and transcriptomic profiling of acute leukemia of ambiguous lineage reveals obscure but clinically important lineage bias

• Zhen-Tang Lao,
• Ling-Wen Ding,
• Omer An,
• Norimichi Hattori,
• Qiao-Yang Sun,
• Kar-Tong Tan,
• Anand Mayakonda,
• Wong Gee Chuan,
• Vikas Madan,
• De-Chen Lin,
• Henry Yang,
• H. Phillip Koeffler

Affiliations

Zhen-Tang Lao

Cancer Science Institute of Singapore, National University of Singapore, Singapore;Department of Haematology, Singapore General Hospital, Singapore

Ling-Wen Ding

Cancer Science Institute of Singapore, National University of Singapore, Singapore

Omer An

Cancer Science Institute of Singapore, National University of Singapore, Singapore

Norimichi Hattori

Division of Hematology, Department of Medicine, Showa University, Tokyo, Japan

Qiao-Yang Sun

Cancer Science Institute of Singapore, National University of Singapore, Singapore

Kar-Tong Tan

Division of Medical Sciences, Harvard Medical School, Boston, MA. USA

Anand Mayakonda

Cancer Science Institute of Singapore, National University of Singapore, Singapore

Wong Gee Chuan

Department of Haematology, Singapore General Hospital, Singapore

Vikas Madan

Cancer Science Institute of Singapore, National University of Singapore, Singapore

De-Chen Lin

Division of Hematology/Oncology, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA, USA

Henry Yang

Cancer Science Institute of Singapore, National University of Singapore, Singapore

H. Phillip Koeffler

Cancer Science Institute of Singapore, National University of Singapore, Singapore;Division of Hematology/Oncology, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA, USA