Nature Communications (May 2021)

Microsecond fingerprint stimulated Raman spectroscopic imaging by ultrafast tuning and spatial-spectral learning

  • Haonan Lin,
  • Hyeon Jeong Lee,
  • Nathan Tague,
  • Jean-Baptiste Lugagne,
  • Cheng Zong,
  • Fengyuan Deng,
  • Jonghyeon Shin,
  • Lei Tian,
  • Wilson Wong,
  • Mary J. Dunlop,
  • Ji-Xin Cheng

DOI
https://doi.org/10.1038/s41467-021-23202-z
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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The authors employ a polygon-based ultrafast delay scanner and a deep learning framework for acquiring stimulated Raman scattering spectrum with high spectral and temporal resolution. They demonstrate high-speed imaging and tracking of multiple biomolecules in the fingerprint region.