HPLC Screening of Phytoestrogens from Soybeans in Conjunction with Chemometric Data Analysis: A Tool for Selecting the Best Raw Materials for Producing Dietary Supplements for Menopausal Health

Abstract

Soybeans are one of the primary dietary sources of isoflavones - phytoestrogens with numerous benefits to human health, including alleviating menopausal symptoms, reducing the risk of certain types of cancer and many others. This research provides a combined approach of high-performance liquid chromatography and chemometry, which is able to highlight in a fast way the isoflavone content of soybean seeds belonging to different genotypes. The proposed approach can be considered not only for quality control assessment purposes, but also for assisting breeding programs targeted to develop new genotypes with the desired isoflavone content.

Keywords

• menopausal health
• isoflavones
• soybean HPLC