Preparation of No-Carrier-Added 177Lu by DGA Resin Assisted Cyclic Elution

Abstract

A preparation process of No-Carrier-Added (NCA) 177Lu in China Mianyang Research Reactor (CMRR）was investigated. In this work, the key component of the process is DGA resin column which can adsorb Yb(Ⅲ) and Lu(Ⅲ) metal ions in the eluent was added to the purification process of 177Lu. The eluent “on-line” cyclic elution of lanthanide resin column was realized through special flow path connection. The tracer test showed that this technology can effectively reduce the volume of radioactive acid waste liquid generated from purification process of 177Lu. The technology was verified in three batches production, and the primary separation stage reduced the volume of waste liquid above 86%. The NCA 177Lu product prepared by cyclic elution process meets the quality requirements.

Keywords

• no-carrier-added 177lu
• dga resin
• medical isotopes
• 177lu separations