Effects of dietary supplementation of bacteriophage with or without zinc oxide on the performance and gut development of weanling pigs

Abstract

The present study investigates the effect of zinc oxide (ZN), bacteriophage (BAC) or their combination on the growth performance and gut development in weaning pigs. A total of 200 weaned pigs were allotted to four treatments including two levels (0 and 0.34%) of ZN and two levels (0 and 0.10%) of BAC cocktail. Supplementation of both BAC and ZN in the diet improved average daily gain and gain to feed ratio in all three phases. The apparent total tract digestibility (ATTD) of dry matter was consistently increased in BAC. A higher digestibility of dry matter was observed in ZN group at phase-I and II. The ATTD of crude protein was increased in BAC group at phase-I and III. ZN increased ATTD of crude protein during phase III. In all phases, the population of total anaerobic bacteria, Bifidobacterium spp., Lactobacillus spp., Clostridium spp. and coliforms were higher in BAC and ZN groups with the exception for coliforms in ZN at the end of experiment. The duodenum (p < 0.05) and jejunum (p < 0.01) villus heights were considerably increased in BAC group but the ileal villus height was not affected by the addition of BAC in the diet. Similar increase (p < 0.05) in the duodenal (p = 0.06) and jejunal (p < 0.01) villus heights were also observed in ZN supplemented groups. The overall faecal score was reduced (p < 0.01) by BAC and tended to decrease (p = 0.07) by ZN. Thus both ZN and BAC are useful for improving the performance and gut health in weaning pigs without any interactive effects.

Keywords

• bacteriophages
• growth performance
• gut health
• weanling pigs
• zinc oxide