Quantifying PON1 on HDL with nanoparticle-gated electrokinetic membrane sensor for accurate cardiovascular risk assessment

Sonu Kumar; Nalin Maniya; Ceming Wang; Satyajyoti Senapati; Hsueh-Chia Chang

doi:10.1038/s41467-023-36258-w

Nature Communications (Feb 2023)

Quantifying PON1 on HDL with nanoparticle-gated electrokinetic membrane sensor for accurate cardiovascular risk assessment

Sonu Kumar,
Nalin Maniya,
Ceming Wang,
Satyajyoti Senapati,
Hsueh-Chia Chang

Affiliations

Sonu Kumar: Department of Chemical and Biomolecular Engineering, University of Notre Dame
Nalin Maniya: Department of Chemical and Biomolecular Engineering, University of Notre Dame
Ceming Wang: Department of Chemical and Biomolecular Engineering, University of Notre Dame
Satyajyoti Senapati: Department of Chemical and Biomolecular Engineering, University of Notre Dame
Hsueh-Chia Chang: Department of Chemical and Biomolecular Engineering, University of Notre Dame

DOI: https://doi.org/10.1038/s41467-023-36258-w
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 13

Abstract

Read online

Measuring proteomic subfractions of HDL can help during cardiovascular risk assessment. Here, the authors show, using a Nanoparticle-Gated Electrokinetic Membrane Sensor, the efficacy of Paroxonase 1 on HDL in its ability to diagnose cardiovascular disease compared to other commonly used methods.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal