Frontiers in Cardiovascular Medicine (Jun 2021)

Challenges and Management of Acute Coronary Syndrome in Cancer Patients

  • Isabela Bispo Santos da Silva Costa,
  • Fernanda Thereza de Almeida Andrade,
  • Diego Carter,
  • Vinicius B. Seleme,
  • Maycon Santos Costa,
  • Carlos M. Campos,
  • Ludhmila Abrahão Hajjar,
  • Ludhmila Abrahão Hajjar

DOI
https://doi.org/10.3389/fcvm.2021.590016
Journal volume & issue
Vol. 8

Abstract

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Cancer and cardiovascular disease are the leading causes of mortality in the world. The prevalence of cardiovascular risk factors and coronary artery disease in cancer patients is elevated, and it is associated with high mortality. Several mechanisms, such as the proinflammatory and procoagulant states present in cancer patients, may contribute to these scenarios. Oncological therapy can predispose patients to acute thrombosis, accelerated atherosclerosis and coronary spasm. Treatment decisions must be individualized and based on the cancer history and balancing bleeding and thrombosis risks.

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