Nature Communications (Jun 2022)
SARS-CoV-2 antibody trajectories after a single COVID-19 vaccination with and without prior infection
- Jia Wei,
- Philippa C. Matthews,
- Nicole Stoesser,
- Ian Diamond,
- Ruth Studley,
- Emma Rourke,
- Duncan Cook,
- John I. Bell,
- John N. Newton,
- Jeremy Farrar,
- Alison Howarth,
- Brian D. Marsden,
- Sarah Hoosdally,
- E. Yvonne Jones,
- David I. Stuart,
- Derrick W. Crook,
- Tim E. A. Peto,
- A. Sarah Walker,
- David W. Eyre,
- Koen B. Pouwels,
- The COVID-19 Infection Survey team
Affiliations
- Jia Wei
- Nuffield Department of Medicine, University of Oxford
- Philippa C. Matthews
- Nuffield Department of Medicine, University of Oxford
- Nicole Stoesser
- Nuffield Department of Medicine, University of Oxford
- Ian Diamond
- Office for National Statistics
- Ruth Studley
- Office for National Statistics
- Emma Rourke
- Office for National Statistics
- Duncan Cook
- Office for National Statistics
- John I. Bell
- Office of the Regius Professor of Medicine, University of Oxford
- John N. Newton
- European Centre for Environment and Human Health, University of Exeter
- Jeremy Farrar
- Wellcome Trust
- Alison Howarth
- Nuffield Department of Medicine, University of Oxford
- Brian D. Marsden
- Nuffield Department of Medicine, University of Oxford
- Sarah Hoosdally
- Nuffield Department of Medicine, University of Oxford
- E. Yvonne Jones
- Nuffield Department of Medicine, University of Oxford
- David I. Stuart
- Nuffield Department of Medicine, University of Oxford
- Derrick W. Crook
- Nuffield Department of Medicine, University of Oxford
- Tim E. A. Peto
- Nuffield Department of Medicine, University of Oxford
- A. Sarah Walker
- Nuffield Department of Medicine, University of Oxford
- David W. Eyre
- Big Data Institute, Nuffield Department of Population Health, University of Oxford
- Koen B. Pouwels
- The National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at the University of Oxford
- The COVID-19 Infection Survey team
- DOI
- https://doi.org/10.1038/s41467-022-31495-x
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 9
Abstract
The impact of prior infection on the immune response to COVID-19 vaccination has not been fully characterised. Here, the authors use data from ~100,000 adults in the UK and find that a single vaccine dose in those with prior infection produces a comparable or stronger response to two doses in those without infection.
