Nature Communications (Feb 2022)

Live-dead assay on unlabeled cells using phase imaging with computational specificity

  • Chenfei Hu,
  • Shenghua He,
  • Young Jae Lee,
  • Yuchen He,
  • Edward M. Kong,
  • Hua Li,
  • Mark A. Anastasio,
  • Gabriel Popescu

DOI
https://doi.org/10.1038/s41467-022-28214-x
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 8

Abstract

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Common methods for characterising cell viability involve cell staining with chemical reagents. Here the authors report a method for cell viability assessment that does not require labelling; this uses quantitative phase imaging combined with deep learning.