Journal for ImmunoTherapy of Cancer (Nov 2023)

274 Development of CTX112 a next generation allogeneic multiplexed CRISPR-edited CART cell therapy with disruptions of the TGFBR2 and Regnase-1 genes for improved manufacturing and potency

  • Sarah Cohen,
  • Jacob Waldman,
  • Andrew Dunn,
  • Thao Nguyen,
  • Jonathan Terrett,
  • Brigid Mcewan,
  • Meghna Kuppuraju,
  • Mohammed Ghonime,
  • Robert Chain,
  • Zinkal Padalia,
  • Demetrios Kalaitzidis,
  • Elizabeth Koch,
  • Lauren Zakas,
  • Nivedita Jaishankar,
  • Davis Settipane,
  • Paul Tetteh,
  • Mary-Lee Dequeant,
  • Sushant Karnik,
  • Chandirasegaran Massilamany,
  • Henia Dar,
  • Melanie Allen,
  • Laura Serwer,
  • Melanie Butler-Gauthier,
  • Parin Sripakdeevong,
  • Shashwat Nagar,
  • Yin Tang,
  • Nicole Flanagan,
  • Elaine Huang,
  • Shashwant Phuyal,
  • Erisa Sula,
  • Maria Lei Zhang,
  • Cristian Loaiza,
  • Erin Thorstensen,
  • Keith Steiger,
  • Katie Schum,
  • Kayla Urbaez,
  • Anna Ma,
  • Annie Yang Weaver,
  • Christopher Finch,
  • PK Morrow,
  • Mark Benton

DOI
https://doi.org/10.1136/jitc-2023-SITC2023.0274
Journal volume & issue
Vol. 11, no. Suppl 1

Abstract

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