South African Family Practice (Sep 2022)

A pandemic guided by the SARS-CoV-2 PCR test: What should the clinician know?

  • Avania Bangalee,
  • Kreshalen Govender,
  • Varsha Bangalee

DOI
https://doi.org/10.4102/safp.v64i1.5492
Journal volume & issue
Vol. 64, no. 1
pp. e1 – e4

Abstract

Read online

Amidst an ever-evolving pandemic, the demand for timely and accurate diagnosis of coronavirus disease 2019 (COVID-19) continues to increase. Critically, managing and containing the spread of the disease requires expedient testing of infected individuals. Presently, the gold standard for the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains the polymerase chain reaction (PCR) test. Potential vulnerabilities of this testing methodology can range from preanalytical variables to laboratory-related analytical factors and, ultimately, to the interpretation of results.

Keywords