Fusarium rhinosinusitis post chimeric antigen receptor T-cell therapy

Supavit Chesdachai; Natalia E. Castillo Almeida; Isin Y. Comba; Prasuna Muppa; Matthew J. Thoendel

IDCases (Jan 2021)

Fusarium rhinosinusitis post chimeric antigen receptor T-cell therapy

Supavit Chesdachai,
Natalia E. Castillo Almeida,
Isin Y. Comba,
Prasuna Muppa,
Matthew J. Thoendel

Affiliations

Supavit Chesdachai: Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN, USA; Corresponding author at: Division of Infectious Diseases, Department of Medicine, 200 First Street SW, Rochester, MN, 55905, USA.
Natalia E. Castillo Almeida: Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN, USA
Isin Y. Comba: Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN, USA
Prasuna Muppa: Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Matthew J. Thoendel: Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN, USA; Corresponding author at: Division of Infectious Diseases, Department of Medicine, 200 First Street SW, Rochester, MN, 55905, USA.

Journal volume & issue: Vol. 24
p. e01088

Abstract

Read online

Chimeric antigen receptor T-cell (CAR-T) therapy is a novel treatment for various types of hematologic malignancy. We presented a case of refractory diffuse large B cell lymphoma patient who developed acute invasive fungal rhinosinusitis (AIFR) from Fusarium species after CAR-T therapy. Our photos illustrated the classic clinical, endoscopic, and histopathologic findings of AIFR.

Published in IDCases

ISSN: 2214-2509 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases
Website: http://www.journals.elsevier.com/idcases/

About the journal

Abstract

Keywords