Successful rechallenge with cetuximab after progression with nivolumab for recurrent cervical lymph node metastasis from carcinoma of the tongue

Affiliations

Yasuyuki Asada: Department of Oral and Maxillofacial Surgery Shiga University of Medical Science Shiga Japan
Chitoshi Teramura: Department of Oral and Maxillofacial Surgery Otsu City Hospital Shiga Japan
Takuma Wada: Department of Oral and Maxillofacial Surgery Otsu City Hospital Shiga Japan
Yoshisato Machida: Department of Oral and Maxillofacial Surgery Shiga University of Medical Science Shiga Japan
Shinya Koshinuma: Department of Oral and Maxillofacial Surgery Shiga University of Medical Science Shiga Japan
Gaku Yamamoto: Department of Oral and Maxillofacial Surgery Shiga University of Medical Science Shiga Japan

Abstract

Abstract We can infer that the immunostimulatory effect of nivolumab and reactivation of cetuximab enhance the antitumor effect of the therapy.