Nature Communications (Apr 2019)

Deep brain stimulation of the internal capsule enhances human cognitive control and prefrontal cortex function

  • A. S. Widge,
  • S. Zorowitz,
  • I. Basu,
  • A. C. Paulk,
  • S. S. Cash,
  • E. N. Eskandar,
  • T. Deckersbach,
  • E. K. Miller,
  • D. D. Dougherty

DOI
https://doi.org/10.1038/s41467-019-09557-4
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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Deep brain stimulation (DBS) is a promising treatment for psychiatric disorders, but its mechanism in relieving symptoms is unclear. Here, the authors show that DBS of ventral internal capsule/ventral striatum (VCVS) may act by enhancing prefrontal cortex oscillations that in turn enhance cognitive control.