Biology Direct (Aug 2024)

Wandering about allostery

  • Maurizio Brunori

DOI
https://doi.org/10.1186/s13062-024-00502-0
Journal volume & issue
Vol. 19, no. 1
pp. 1 – 23

Abstract

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Abstract It was a Lucky Strike to be working with Eraldo Antonini on hemoglobin and myoglobin when Jeffries Wyman arrived in Rome in 1961. I found myself connected with a number of creative scientists when the concept of allosteric control was conceived and gifted to the life science community. In retrospect, this was a demonstration of the skill and imagination of a few intelligent scientists that I happened to be close to. Those talents demonstrated the power of creativity as pictured by the motto “Mens agitat molem”; a celebration of humanism and intellect that paved the way to novel discoveries in the field of structure function relationships in proteins. I have presented hereby some of the events and the people as emerged from my memory over three decades of exciting scientific life.