Relay cross metathesis reactions of vinylphosphonates

Abstract

Dimethyl (β-substituted) vinylphosphonates do not readily undergo cross metathesis reactions with Grubbs catalyst and terminal alkenes. However, the corresponding mono- or diallyl vinylphosphonate esters undergo facile cross metathesis reactions. The improved reactivity is attributed to a relay step in the cross metathesis reaction mechanism.

Keywords

• centrolobine
• metathesis
• organo phosphorus
• relay
• vinyl phosphonate