A rare case of acute myeloid leukemia with ARHGEF12 (LARG, 11q23.3) and MAPRE1 (EB1, 20q11.21) fusion gene in an elderly patient

Macarie Ioan; Tripon Florin; Dorcioman Bogdana; Macarie Melania

doi:10.2478/rrlm-2020-0009

Romanian Journal of Laboratory Medicine (Jan 2020)

A rare case of acute myeloid leukemia with ARHGEF12 (LARG, 11q23.3) and MAPRE1 (EB1, 20q11.21) fusion gene in an elderly patient

Macarie Ioan,
Tripon Florin,
Dorcioman Bogdana,
Macarie Melania

Affiliations

Macarie Ioan: George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania
Tripon Florin: George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania
Dorcioman Bogdana: Targu Mures Clinical County Emergency Hospital, Central Laboratory, Romania
Macarie Melania: George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania

DOI: https://doi.org/10.2478/rrlm-2020-0009
Journal volume & issue: Vol. 28, no. 1
pp. 99 – 106

Abstract

Read online

Introduction. We report one elderly patient diagnosed with a rare subtype of acute myeloid leukemia (AML) and also with a very rare fusion gene involving ARHGEF12 (LARG, 11q23.3) and MAPRE1 (EB1, 20q11.21) genes.

Published in Romanian Journal of Laboratory Medicine

ISSN: 2284-5623 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Medicine
Website: https://sciendo.com/journal/RRLM

About the journal

Abstract

Keywords